SMALP network  
SMALP Membrane Protein Conference

Membrane Protein Conference on December 1, 2026

Our next International Membrane Protein Conference will be held on Tuesday Dec. 1, 2026 from 2-5pm CET (8-11 am ET) and will feature a series of about eight 20 minute talks covering the latest findings about membrane structure and function, lipid-protein interactions as well as advances for purification and resolution of native membrane assemblies, as depicted above by data from the speakers.

Feel free to nominate a speaker with an exciting story to tell here.

We seek to explore and disseminate new concepts and tools in the field of membrane protein biology. Free student tickets are available, and registration is 20 or 30 euros for academics or industry to help cover our costs as an independent organization run by scientists for their fellow scientists. Dip in and out of this zoom meeting as needed and receive the recordings afterwards.


Membrane Protein Conference Videos and Attendees on Sept 15, 2026

14:00 CET Introductions, pose any questions, sharing of tips and tricks

Session 1 chaired by Gestél Kuyler, CEO & co-Founder, Nanosene

Salma Dienta Salsabila14:10 Salma Dienta Salsabila, PhD Student with Jungwook Kim, Gwangju Institute of Science and Technology, who published Structural mechanism of membrane-associated cytidine diphosphate diacylglycerol diphosphatase in Escherichia coli in Int J Biol Macromol.

14:30 Alexej KedrovAssociate Professor, University of Düsseldorf on the substrate-induced assembly and functional mechanism of the bacterial membrane protein insertase SecYEG-YidC using nanodiscs and cryo-EM, which was published in EMBO J.

Meseret Haile14:50 Meseret Haile, PhD Student with Chi-Min Ho, Assistant Professor of Microbiology & Immunology at Columbia University, and recently published structural basis for host membrane binding and remodeling by invading malaria parasites in Cell, having purified the native complex directly from invasion-stalled parasites on host cells for CryoEM.
15:10 Break and open discussion

Session 2 chaired by Orestes Karatzas, MSc Student, Biochemistry Dept, UofA

Bernadette Byrne15:15 Bernadette Byrne, Professor in Molecular Membrane Biology, Imperial College London, focusses on eukaryotic membrane protein structure and function, with emphasis on transporters and receptors, and will give a talk on the RAMP Lipid Screen.


Shiv K. Sah Teli15:35 Shiv K. Sah Teli, Postdoc­toral Re­searcher with Juha Huiskonen, Laboratory of Structural Biology, University of Helsinki, who published Gating Mechanism of the Human Connexin 45 Gap Junction in bioRxiv.

15:55 Break and open discussion

Session 3 chaired by Manan Upadhyaya, Researcher, Biochemistry Dept, UofA

16:00 Surbhi Dhingra, Postdoctoral Fellow with Kenton Swartz, National Institute of Neurological Disorders and Stroke, NIH, who recently published Mechanisms of ligand recognition and channel opening for P2X2 receptors in lipid nanodiscs in Science Advances.


Hayarpi Torosyan16:20 Hayarpi Torosyan, Postdoctoral Scholar with Kliment A. Verba and Natalia Jura at University of California, San Francisco, who recently published Structures of the PI3Kα/KRas complex on lipid bilayers reveal molecular mechanisms of PI3Kα activation in Mol Cell.


Moitrayee Bhattacharyya16:40 Moitrayee Bhattacharyya, Associate Professor of Pharmacology, Department of Pharmacology, School of Medicine, Yale University, on Single molecule microscopy and cryo-EM with native nanodiscs in understanding neurodegeneration and pain.

17:00 Discussion and close


SMALP 2026:

2nd International Conference on Native Membrane Nanoparticles

Location: Stellenbosch Institute for Advanced Studies

Dates: November 16-20, 2026

Lead Organizer: Bert Klumperman

Deadline for abstracts for talks and posters: 15 August

Early bird registration closes on 27 August


Fill out our short Conference Evaluation Form, we value your feedback.


Speaker Awards

Sponsored by Nanosene. Our previous winners:


Background on SMALP

The SMALP network is an open forum initiated by the international research community. We are developing and using amphipathic copolymers as alternatives to conventional detergents, which tend to dissociate, destabilize and deactivate native membrane proteins.

SMA polymer

A variety of amphipathic polymers such as styrene maleic acid have been found to directly and spontaneously solubilize proteins and bound lipids from membranes when activated. This provides opportunities for understanding and exploiting the structure and function of native membrane protein complexes.

As SMALP technology is relatively new, the participation of the wider community and sharing of new ideas and practices amongst researchers is the best way to ensure continued rapid development of the field.

The SMALP network offers polymers, methods and meetings to support the growing community of scientists and companies interested in the preparation of membrane nanodiscs formed by polymers including styrene maleic acid for biological research and drug discovery applications.

Register for a day of insightful talks from experts in the structural biology and functions of membrane proteins and nanodisc development, discussions with academic and industry leaders, and enjoy breakfast, lunch and coffee breaks on us.

These events are offered to bring together academic and industry experts, postdocs and students who are interested in membrane protein structural biology, lipidomics, proteomics, target discovery and biophysical analysis of bilayers and amphipathic polymers.

We welcome researchers from across academia and industry to join us in lively discussions and debate about the latest advances in native nanodiscs, membrane proteins, polymer chemistry, lipid biophysics, structural biology, and applications including drug discovery and delivery.